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SDZ SER 082 fumarate

Cat. No. M7287

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SDZ SER 082 fumarate Structure

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Quality Control & Documentation
Biological Activity

SDZ SER 082 富马酸盐是一种选择性 5-HT2B/2C 受体拮抗剂,对 5-HT1A 受体具有低亲和力。抑制[3H]-美舒肾上腺素与5-HT2C受体的结合,pKD为7.8。抑制大鼠眼底中5-HT2B介导的反应(pKB = 7.34)。

Chemical Information
Molecular Weight 344.41
Formula C15H20N2.C4H4O4
CAS Number 1417343-80-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Beaujouan, et al. Br J Pharmacol. Higher potency of RP 67580, in the mouse and the rat compared with other nonpeptide and peptide tachykinin NK1 antagonists.

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