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Schizandrin-A

Cat. No. M4244

All AbMole products are for research use only, cannot be used for human consumption.

Schizandrin-A Structure
Synonym:

Schizandrin-A; Wuweizisu-A; Deoxyschizandrin

Size Price Availability Quantity
10mg USD 70  USD70 In stock
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Quality Control & Documentation
Biological Activity

Schizandrin-A, a lignan from Schisandra chinensis, is also a novel heat shock factor 1 (HSF1) inhibitor that effectively inhibits the induction of HSF1 target proteins such as heat shock protein 70 (HSP70) and HSP27. In addition, Schizandrin-A also regulates lipid metabolism and oxidative stress and possesses neuroprotective activity.

Chemical Information
CAS Number 61281-38-7
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] No authors listed. Braz J Med Biol Res. Retraction notice for: "Schizandrin A exerts anti-tumor effects on A375 cells by down-regulating H19" [Braz J Med Biol Res (2019) 52(10): e8385]

[2] Qi Wang, et al. Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice

[3] Shuo Ni, et al. Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling

[4] Huiling Yan, et al. Schizandrin A inhibits cellular phenotypes of breast cancer cells by repressing miR-155

[5] Bing-Chen Chen, et al. Schizandrin A exhibits potent anticancer activity in colorectal cancer cells by inhibiting heat shock factor 1

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  Catalog
Abmole Inhibitor Catalog




Keywords: Schizandrin-A, Schizandrin-A; Wuweizisu-A; Deoxyschizandrin supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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