Free shipping on all orders over $ 500

BMP signaling agonist sb4

Cat. No. M10455

All AbMole products are for research use only, cannot be used for human consumption.

BMP signaling agonist sb4 Structure
Synonym:

SB-4

Size Price Availability Quantity
10mM*1mL in DMSO USD 45  USD45 In stock
1mg USD 25  USD25 In stock
5mg USD 40  USD40 In stock
10mg USD 56  USD56 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

BMP signaling agonist sb4 (SB-4) is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM. BMP signaling agonist sb4 activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. 

Chemical Information
Molecular Weight 320.20
Formula C14H10BrNOS
CAS Number 100874-08-6
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Eleftherios Pelechas, et al. Expert Opin Biol Ther. Etanercept biosimilar SB-4

[2] Shayna T J Bradford, et al. J Biol Chem. High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds

Related TGF-beta/Smad Products
A 83-01 sodium

A 83-01 sodium is a potent inhibitor of TGF-β type I receptors ALK5, ALK4, and ALK7, inhibiting ALK5, ALK4, and ALK7-induced transcription with IC50 values of 12 nM, 45 nM, and 7.5 nM, respectively.

Myristoyl tetrapeptide-12

Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA.

H-Leu-Ser-Lys-Leu-OH

H-Leu-Ser-Lys-Leu-OH (LSYL) is a latency-associated peptide at the amino terminus of LAP, with inhibitory effect on TGF-β1 activation.

SY-LB-35

SY-LB-35 is a potent bone morphogenetic protein (BMP) receptor agonist.

DT-6

DT-6 is an effective TGF-β1 inhibitor.

  Catalog
Abmole Inhibitor Catalog




Keywords: BMP signaling agonist sb4, SB-4 supplier, TGF-beta/Smad, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.