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SB 206553 hydrochloride

Cat. No. M7253

All AbMole products are for research use only, cannot be used for human consumption.

SB 206553 hydrochloride Structure

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Quality Control & Documentation
Biological Activity

SB 206553 hydrochloride is a potent and selective 5-HT2B/5-HT2C receptor antagonist (rat 5-HT2B pA2 = 8.89, human 5-HT2C pKi = 7.92). Displays > 80-fold selectivity over all other 5-HT receptor subtypes and a variety of other receptors (pKi < 6). Centrally active following oral administration in vivo.

Chemical Information
Molecular Weight 328.8
Formula C17H16N4O.HCl
CAS Number 1197334-04-5
Solubility (25°C) DMSO 32.88 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Rundfeldt, et al. J Pharmacol Exp Ther. Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice Comparison of diazepam, bretazenil and abecarnil.

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