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Samatasvir

Cat. No. M28156

All AbMole products are for research use only, cannot be used for human consumption.

Samatasvir Structure
Synonym:

IDX719; IDX18719

Price and Availability

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Quality Control & Documentation
Biological Activity

Samatasvir (IDX71) is a potent, orally active NS5A inhibitor of HCV replication. Samatasvir is effective and selective against infectious HCV and replicons, with EC50s falling within a tight range of 2 to 24 pM in genotype 1 through 5 replicons.

Chemical Information
Molecular Weight 885.06
Formula C47H48N8O6S2
CAS Number 1312547-19-5
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic)
Storage 4°C, protect from light
References

[1] J P Bilello, et al. Antimicrob Agents Chemother. In vitro activity and resistance profile of samatasvir, a novel NS5A replication inhibitor of hepatitis C virus

[2] Bradley Vince, et al. J Hepatol. A randomized, double-blind, multiple-dose study of the pan-genotypic NS5A inhibitor samatasvir in patients infected with hepatitis C virus genotype 1, 2, 3 or 4

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Keywords: Samatasvir, IDX719; IDX18719 supplier, Anti-infection, inhibitors, activators

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