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Salvinorin A

Cat. No. M8191

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Salvinorin A Structure

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Quality Control & Documentation
Biological Activity

Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.

Chemical Information
Molecular Weight 432.46
Formula C23H28O8
CAS Number 83729-01-5
Solubility (25°C) DMSO: ≥10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Qiyang Shou, et al. Salvinorin A inhibits ovalbumin-stimulated allergic rhinitis and RBL-2H3 cells degranulation

[2] Patrick Zimdars, et al. A Protecting-Group-Free Synthesis of (-)-Salvinorin A

[3] Andreia Machado Brito-da-Costa, et al. Pharmacokinetics and Pharmacodynamics of Salvinorin A and Salvia divinorum: Clinical and Forensic Aspects

[4] Katarzyna Socała, et al. Salvinorin A Does Not Affect Seizure Threshold in Mice

[5] Jeremy J Roach, et al. A review of salvinorin analogs and their kappa-opioid receptor activity

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Keywords: Salvinorin A supplier, inhibitors, activators

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