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SAfit2 is a potent inhibitor of FK506-binding protein 51 (FKBP51) with a Ki value of 6 nM. SAfit2 has been used as a potential agent in the study of major depression, obesity, and chronic pain.
| Molecular Weight | 802.99 |
| Formula | C46H62N2O10 |
| CAS Number | 1643125-33-0 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | Powder -20°C |
| Related FKBP (FK506-binding protein) Products |
|---|
| dTAGV-1 hydrochloride
dTAGV-1 hydrochloride is the hydrochloride form of dTAGV-1 that is a small molecule degrader of FKBP12. |
| Suc-Ala-Leu-Pro-Phe-pNA
Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA) is a substrate of FK-506 binding protein (FKBP). |
| RapaBlock
RapaBlock is a potent, non-immunosuppressive and brain-impermeable FKBP12 ligand. |
| FKBP51F67V-selective antagonist Ligand2
FKBP51F67V-selective antagonist Ligand2 is a potent FKBP51 F67V-selective antagonist ligand. |
| dTAGV-1-NEG TFA
dTAGV-1-NEG TFA is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1-NEG TFA is an FKBP12F36V-selective degrader. |
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