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S-Adenosyl-L-Methtonine

Cat. No. M44003

All AbMole products are for research use only, cannot be used for human consumption.

S-Adenosyl-L-Methtonine Structure
Size Price Availability Quantity
5mg USD 50  USD50 In stock
10mg USD 75  USD75 In stock
50mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

S-Adenosyl-L-Methtonine is an important metabolite that is ubiquitous in all biological cells. SAM can participates in the transmethylation reaction, transsulfurization reaction and transaminopropyl reaction of cells, and plays an irreplaceable role in the methylation modification, sulfur group storage and transfer of important intracellular molecules. S-Adenosyl-L-methionine has antidepressant activity, it is endogenously produced from methionine and ATP by the action of methionine adenylyltransferase, and is an important methyl donor with oral viability capable of being used in liver disease and osteoarthritis research.

Chemical Information
Molecular Weight 398.44
Formula C15H22N6O5S
CAS Number 17176-17-9
Solubility (25°C) Water 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Meijing Li, et al. Sheng Wu Gong Cheng Xue Bao. [Microbial production of S-adenosyl-l-methionine: a review]

[2] Mangal S Kadam, et al. J Biomol Struct Dyn. S-adenosyl-l-methionine interaction signatures in methyltransferases

[3] A Yu Rudenko, et al. Mol Biol (Mosk). [Analogs of S-Adenosyl-L-Methionine in Studies of Methyltransferases]

[4] Srivani Sistla, et al. Crit Rev Biochem Mol Biol. S-Adenosyl-L-methionine-dependent restriction enzymes

[5] R J Baldessarini. Am J Med. Neuropharmacology of S-adenosyl-L-methionine

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