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S 32826 is a inhibitor of autotaxin (IC50 = 9 nM). Displays similar inhibitory effects at all three autotaxin isoforms (α, β and γ). Exhibits no affinity for lysophosphatidic acid receptor 1 (LPA1) at concentrations up to 10 μM. Inhibits LPA release from adipocytes (IC50 = 90 nM).
| Molecular Weight | 441.45 |
| Formula | C21H34NO4PNa2 |
| CAS Number | 1103672-43-0 |
| Solubility (25°C) | 1eq. NaOH 44.15 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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