Free shipping on all orders over $ 500

Rutaecarpine

Cat. No. M4437
Rutaecarpine Structure
Synonym:

Rutecarpine

Size Price Availability Quantity
10mg USD 60  USD60 In stock
20mg USD 90  USD90 In stock
50mg USD 180  USD180 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Rutaecarpine is a delayed rectifier K+ channel blocker, inhibits platelet aggregation.

Chemical Information
Molecular Weight 287.32
Formula C18H13N3O
CAS Number 84-26-4
Solubility (25°C) DMSO 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Tae Won Jeon, et al. Toxicol Lett. Immunosuppressive effects of rutaecarpine in female BALB/c mice

[2] T C Moon, et al. Inflamm Res. A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa

Related COX Products
Birch triterpenes

Birch triterpenes is a cyclooxygenase-2 (COX-2) inhibitor that can be used in studies related to epidermolysis bullosa.

Naproxcinod

Naproxcinod is a first-of-its-kind (first-in-class) cyclooxygenase-inhibiting nitric oxide donors (CINODs) with analgesic and anti-inflammatory activity for studies related to osteoarthritis and inflammation.

Hamaudol

Hamaudol is a chromone isolated from Saposhnikovia divaricata.

(±)-Catechin

(±)-Catechin (rel-Cianidanol) is the racemate of Catechin.

PYZ18

PYZ18 is a selective COX-2 inhibitor with an IC50 of 7.07 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Rutaecarpine, Rutecarpine supplier, COX, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.