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rTRD01

Cat. No. M42968

All AbMole products are for research use only, cannot be used for human consumption.

rTRD01 Structure

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Biological Activity

rTRD01 is a TDP-43 ligand that binds to TDP-43’s RRM1 and RRM2 domains (Kd=89 uM for TDP-43102–269).

Chemical Information
Molecular Weight 344.38
Formula C18H21FN4O2
CAS Number 1332175-56-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Liberty François-Moutal et al. ACS Chem Biol. Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)

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