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Rp-8-pCPT-cGMPS sodium is a pKG inhibitor (Ki values are 0.45, 0.5 and 0.7 μM for PKGIβ, PKGIα and PKGII respectively). Exhibits selectivity for PKG over PKA and Epac-1. Reduces LTP in hippocampal slices in vitro.
| Molecular Weight | 525.86 |
| Formula | C16H14ClN5NaO6PS2 |
| CAS Number | 208445-07-2 |
| Solubility (25°C) | DMSO 52.59 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related PKG Products |
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| PKG Substrate
PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG). |
| PKG inhibitor peptide
PKG inhibitor peptide is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM. |
| Vasonatrin Peptide (VNP)
Vasonatrin Peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). |
| G-Subtide
G-Subtide is a G-substrate peptide localized in Purkinje cells of the cerebellum. |
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