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RNF5 inhibitor inh-02 is a potent inhibitor of E3 ubiquitin ligase RNF5/RMA1. RNF5 inhibitor inh-02 leads to significant F508del-CFTR rescue (EC50=2.2 uM) in bronchial epithelial cells homozygous for the F508del mutation. RNF5 inhibitor inh-02 can be used for cystic fibrosis research.
| Molecular Weight | 384.5 |
| Formula | C23H20N4S |
| CAS Number | 324579-65-9 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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