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Rimantadine is an oral antiviral compound used for prevention and research on influenza A virus infection. Rimantadine has the same preventive effect as amantadine, but is less likely to cause adverse reactions. Rimantadine hydrochloride is an RNA synthesis inhibitor and antiviral agent used in the prevention and treatment of influenza. Rimantadine hydrochloride is the hydrochloride form of rimantadine, which is a cycloamine and methylmethyl derivative with antiviral activity. Although the exact mechanism of action of rimantadine is unknown, it appears to have an antiviral effect on influenza A viruses by interfering with the function of the transmembrane domain of the viral M2 protein. This prevents the virus from uncoating and subsequently releasing infectious viral nucleic acid into the cytoplasm of the infected cell.
Molecular Weight | 215.76 |
Formula | C12H22ClN |
CAS Number | 1501-84-4 |
Form | Solid |
Solubility (25°C) | DMSO |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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