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Remacemide hydrochloride is a non-competitive NMDA receptor antagonist; blocks ion channel and allosteric modulatory site (IC50 = 8 - 68 mM). Anticonvulsant in vivo and metabolizes to a more potent desglycine analog. Weakly blocks voltage-dependent Na+ channels (IC50 = 161 mM).
| Molecular Weight | 304.82 |
| Formula | C17H20N2O.HCl |
| CAS Number | 111686-79-4 |
| Solubility (25°C) | Water 30.48 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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