All AbMole products are for research use only, cannot be used for human consumption.
Vascular endothelial growth factor (VEGF/VEGF-A) is originally known as vascular permeability factor (VPF). VEGF-As are endothelial cell-specific mitogens with angiogenic and vascular permeability-inducing properties. It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. The active form of rVEGF-A164 is either a homodimeric or heterodimeric polypeptides which bind to the transmembrane tyrosine kinases receptors FLT1, FLK1 or KDR or to the non-tyrosine kinase neuropilin receptors NRP1/2.
Recombinant Rat Vascular Endothelial Growth Factor A expressed the target gene encoding Ala27-Arg190(Ala36Thr).
Measured in a cell proliferation assay using HUVEC cells, the ED50 is < 4.0 ng/ml, corresponding to a specific activity of >2.5 × 105 units/mg.
Accession: P16612-2
Apparent Molecular Weight: 35~48 kDa, on SDS-PAGE under non-reducing conditions
Endotoxin < 0.2 EU/µg
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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