All AbMole products are for research use only, cannot be used for human consumption.
Vascular endothelial growth factor (VEGF/VEGF-A) is originally known as vascular permeability factor (VPF). VEGF-As are endothelial cell-specific mitogens with angiogenic and vascular permeability-inducing properties. It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. The active form of rVEGF-A164 is either a homodimeric or heterodimeric polypeptides which bind to the transmembrane tyrosine kinases receptors FLT1, FLK1 or KDR or to the non-tyrosine kinase neuropilin receptors NRP1/2.
Recombinant Rat Vascular Endothelial Growth Factor A expressed the target gene encoding Ala27-Arg190(Ala36Thr).
Measured in a cell proliferation assay using HUVEC cells, the ED50 is < 4.0 ng/ml, corresponding to a specific activity of >2.5 × 105 units/mg.
Accession: P16612-2
Apparent Molecular Weight: 35~48 kDa, on SDS-PAGE under non-reducing conditions
Endotoxin < 0.2 EU/µg
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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