All AbMole products are for research use only, cannot be used for human consumption.
Hepatocyte growth factor, also known as HGF, belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, and acts as a multi-functional cytokine on cells of mainly epithelial origin. HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types.
The recombinant rat HGF consists of 696 amino acids and has a predicted molecular mass of 79.3 kDa. A DNA sequence encoding the rat HGF (Met1-Leu728) was expressed.
Measured in a cell proliferation assay using Mv-1-1u mink lung epithelial cells, the ED50 for this effect is typically 1-6 ng/mL.
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 92 kDa, reducing conditions
Lyophilized from sterile PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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