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Thioredoxin/SASP Protein participates in a variety of redox reactions and can use its active dithiol center for reversible oxidation and disulfide bond formation. It catalyzes important dithiol-disulfide exchanges and plays a key role in the S-nitrosylation of cysteine residues in response to intracellular nitric oxide. In addition, TXN inhibits CASP3 activity by nitrosylating its active site cysteine and may also modulate FOS/JUN AP-1 DNA binding activity and influence interleukin 2 receptor expression.
The recombinant mouse Txn consists of 105 amino acids and predicts a molecular mass of 11.7 KDa. A DNA sequence encoding the mouse Txn (Met1-Val105) was expressed.
Measured by its ability to catalyze the reduction of insulin. The reaction leads to precipitation, which can be measured by absorbance at 650 nm. The specific activity is >4 A650/min/mg.
Accession# P10639
Apparent molecular weight：15 KDa, reducing conditions
Lyophilized from sterile PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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