Free shipping on all orders over $ 500

Recombinant Mouse/Rat TGF-beta 2 Protein (Mammalian)

Cat. No. M54564
Recombinant Mouse/Rat TGF-beta 2 Protein (Mammalian) Structure
Synonym:

TGFB2; TGFβ2; transforming growth factor beta-2

Size Price Availability Quantity
10ug USD 265  USD265 In stock
50ug USD 750  USD750 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

Recombinant Mouse/Rat TGF-beta 2 expressed the target gene encoding Ala303-Ser414.

Immobilized Mouse TGFBR2-Fc at 10 μg/ml (100 μl/well) can bind Mouse/Rat TGF-beta 2, the ED50 of Mouse TGFBR2-Fc is 0.136 ug/ml.


Accession: P27090

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 12 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 4mM HCl.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in 4mM HCl up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Related Recombinant Proteins Products
Recombinant Human USP14 (E.coli, N-6His)

USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1.

Recombinant Human EpCAM/Trop-1 (Mammalian, C-Fc)

Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein. EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells.

Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli, aa 18-169, His Tag)

The recombinant human IL1F9 consists of 168 amino acids and predicts a molecular mass of 19.1 KDa. A DNA sequence encoding the mature form of human IL1F9 (Ser18-Asp169) was expressed with a polyhistide tag at the N-terminus.

Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli)

The recombinant human IL1F9 consisting of 169 amino acids and has a calculated molecular mass of 18.9 kDa. A DNA sequence encoding the human IL-1F9 isoform 1 (Met 1-Asp 169) was expressed.

Recombinant Human APOL1 Protein (Baculovirus-Insect, C-His)

APOL1, also known as apolipoprotein L1, belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body.

  Catalog
Abmole Inhibitor Catalog




Keywords: Recombinant Mouse/Rat TGF-beta 2 Protein (Mammalian), TGFB2; TGFβ2; transforming growth factor beta-2 supplier, Recombinant Proteins, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.