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Lymphotoxin Beta Receptor is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs. The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors.
Recombinant Mouse Lymphotoxin Beta Receptor expressed the target gene encoding Ser28-Pro218 with a human IgG1 Fc tag at the C-terminus.
Loaded Mouse LTBR-Fc on Protein A Biosensor, can bind Human LIGHT-His with an affinity constant of 0.81 nM as determined in BLI assay.
Accession: P50284
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 61 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Form | Lyophilized powder |
Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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