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Mouse Leukemia inhibitory factor (LIF) is a secreted protein belonging to the LIF /OSM family. LIF is involved in many physiological processes, including development, hematopoiesis, bone metabolism and inflammation. It has the ability to induce terminal differentiation of leukemia cells. Its activities include inducing hematopoietic differentiation of normal and myeloid leukemia cells, inducing neuronal differentiation, and stimulating acute phase protein synthesis of hepatocytes.
The ability to induce the activity of the STAT reporter factor in 293F human embryonic kidney cells was determined, the ED50 of this effect was 187 ng/mL.
Recombinant Mouse Leukemia Inhibitory Factor expressed the target gene encoding Ser24-Phe203.
Accession: P09056
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 18 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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