All AbMole products are for research use only, cannot be used for human consumption.
Species: Mouse
Expression system: E. coli
Purity: SDS-PAGE, > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: ~ 9kda, sds-page under reduction conditions
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.
Biological activity: EC50 value of MOUSE IP-10 against Cho-K1 /Gα15/mCXCR3 cells (human Gα15 and mouse CXCR3 were stably expressed in Cho-K1 cells) was less than 2.0 μ G/mL. Other cell types expressing IP-10 include activated T lymphocytes, spleen cells, keratinocytes, osteoblasts, astrocytes, and smooth muscle cells. Ip-10 is also expressed in psoriasis and leprosy lesions. The mouse homolog crG-2 of human IP-10 has been cloned and shown to share approximately 67% of the amino acid sequence with human IP-10. This chemokine works by binding to the cell surface chemokine receptor CXCR3. Ip-10 is thought to have a variety of effects, such as attracting monocytes and T cells to chemotherapy, promoting T cell adhesion to endothelial cells, anti-tumor activity, and inhibiting bone marrow colony formation and angiogenesis.
| Solubility (25°C) | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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