All AbMole products are for research use only, cannot be used for human consumption.
Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a multipotent cytokine involved in both pro-inflammatory and anti-inflammatory responses. It is mainly produced by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to the IL-6 receptor (IL-6R), triggering the binding of IL-6R to GP130 and inducing signal transduction via JAK and STATs.
It stimulates B cell differentiation and antibody production, myeloma and plasma cell tumor growth, and nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction and released into the blood stream to help break down fats and improve insulin resistance.
Measured in a bioassay using 7TD1 cells, the ED50 is < 3.0 pg/ml.
Accession: P08505
Apparent Molecular Weight: 24~26 kDa, under reducing conditions.
Endotoxin < 0.2 EU/μg
Lyophilized after extensive dialysis against PBS.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
| Storage | Stable for up to 12 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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