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Recombinant Mouse IL-3 (E. coli)

Cat. No. M21210

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse IL-3 (E. coli) Structure
Synonym:

IL3; interleukin 3; IL-3; MCGF

Size Price Availability Quantity
10ug USD 190  USD190 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Interleukin-3 (IL-3) is a polymorphic cytokine belonging to the interleukin family. IL-3 is also called multi-colony stimulating factor since it stimulates the development and colony formation of multiple lineages of hematopoietic cells by activating intracellular pathways such as Ras-Raf-ERK and JAK/STAT. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family.

Recombinant Mouse Interleukin-3 (IL-3) expressed the target gene encoding Asp33-Cys166.

Measured by a cell proliferation assay using M-NFS-60 cells, the ED50 is < 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 107 units/mg.


Accession: P01586

Endotoxin < 0.2 EU/µg

Apparent Molecular Weight: ~15.2 kDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Michael Dougan, et al. Immunity. GM-CSF, IL-3, and IL-5 Family of Cytokines: Regulators of Inflammation

[2] Kerstin Renner, et al. JCI Insight. IL-3 promotes the development of experimental autoimmune encephalitis

[3] Kerstin Renner, et al. Kidney Int. IL-3 contributes to development of lupus nephritis in MRL/lpr mice

[4] A Kusumi, et al. Gan To Kagaku Ryoho. [Interleukin 3 (IL-3)]

[5] T Takaishi, et al. Int Arch Allergy Immunol. Mouse IL-3 induces histamine release from mouse peritoneal mast cells

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Keywords: Recombinant Mouse IL-3 (E. coli), IL3; interleukin 3; IL-3; MCGF supplier, Cytokines and Growth Factors, inhibitors, activators

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