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Recombinant Mouse IL-22 (Mammalian, C-mFc)

Cat. No. M55364

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse IL-22 (Mammalian, C-mFc) Structure
Synonym:

Interleukin-22

Size Price Availability Quantity
10ug USD 170  USD170 In stock
50ug USD 470  USD470 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Interleukin-22 (IL-22) is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively.

Recombinant Mouse Interleukin-22 expressed the target gene encoding Leu34-Val179 with a mouse IgG1 Fc tag at the C-terminus.

Measure by its ability to induce IL-10 secretion in COLO205 cells, the ED50 for this effect is <0.5 ng/mL.


Accession: Q9JJY9

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 50-65 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
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Keywords: Recombinant Mouse IL-22 (Mammalian, C-mFc), Interleukin-22 supplier, Recombinant Proteins, inhibitors, activators

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