All AbMole products are for research use only, cannot be used for human consumption.
Interleukin-22 (IL-22) is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively.
Recombinant Mouse Interleukin-22 expressed the target gene encoding Leu34-Val179 with a mouse IgG1 Fc tag at the C-terminus.
Measure by its ability to induce IL-10 secretion in COLO205 cells, the ED50 for this effect is <0.5 ng/mL.
Accession: Q9JJY9
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 50-65 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| Related Recombinant Proteins Products |
|---|
| Recombinant Human METRNL Protein (E. coli, N-His)
METRNL (Meteorin-like protein) is a hormone, released after physical activity (in skeletal muscle) or exposure to cold (in adipose tissue), that induces energy rate. METRNL stimulates energy rate correlate with white fat browning and raise glucose tolerance. The protein stimulates different types of immune cells to enter the fat tissue and start their prothermogenic actions. |
| Recombinant Human HK2 Protein (E. coli, N-His)
Hexokinase 2 (HK2) is a rate-determining enzyme in aerobic glycolysis, a process upregulated in tumor cells. HK2 expression is controlled by various transcription factors and epigenetic alterations and is heterogeneous in hepatocellular carcinomas (HCCs). |
| Recombinant Human HK2 Protein (Baculovirus-Insect, C-His)
Hexokinase 2 (HK2) is a rate-determining enzyme in aerobic glycolysis, a process upregulated in tumor cells. HK2 expression is controlled by various transcription factors and epigenetic alterations and is heterogeneous in hepatocellular carcinomas (HCCs). |
| Recombinant Human HER2 Protein (HEK293, C-6His)
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and differentiation. |
| Recombinant Mouse Growth Hormone (E. coli)
Somatotropin (GH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
