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Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenitors and introduced as a putative placental mediator of embryonic development. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker.
Recombinant Mouse Growth Differentiation Factor 15 expressed the target gene encoding Ser189-Ala303 with a 8His, Flag tag at the N-terminus.
Accession: Q9Z0J7
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 14-16 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in 4mM HCl up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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