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FABP4 is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure.
The recombinant mouse FABP4 comprises 143 amino acids and has a calculated molecular mass of 16 kDa. A DNA sequence encoding the mouse FABP4 (Met 1-Ala 132) is expressed with a C-terminal polyhistidine tag.
Endotoxin < 1 EU/µg
Apparent Molecular Weight: ~15 kDa, reducing conditions
Lyophilized from sterile PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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