Free shipping on all orders over $ 500

Recombinant Mouse Apolipoprotein E (Mammalian, C-6His)

Cat. No. M45091

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse Apolipoprotein E (Mammalian, C-6His) Structure
Synonym:

Apo-E; APOE

Size Price Availability Quantity
10ug USD 180  USD180 In stock
50ug USD 660  USD660 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Apolipoprotein E (Apo-E) is a member of the apolipoprotein A1/A4/E family. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. Apolipoprotein E (Apo-E) can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. 

Recombinant Mouse Apolipoprotein E expressed the target gene encoding Glu19-Gln311 with a 6His tag at the C-terminus. 


Accession: P08226

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 30-40 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Claudia Marino, et al. Alzheimers Dement. APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation

[2] Eu Jeong Ku, et al. Int J Mol Sci. The Anti-Atherosclerosis Effect of Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, in Apolipoprotein E Knockout Mice

[3] Martin Maeng Bjørklund, et al. Circ Res. Induction of atherosclerosis in mice and hamsters without germline genetic engineering

[4] Akin Akinc, et al. Mol Ther. Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms

[5] D M Holtzman, et al. J Clin Invest. Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

Related Recombinant Proteins Products
Recombinant Mouse Growth Hormone (E. coli)

Somatotropin (GH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.

Recombinant Human Activin A Protein (HEK293)

Recombinant Activin A protein is a multifunctional cytokine belonging to transforming growth factor β (TGF β) superfamily. It is associated with a variety of pathophysiological processes, including inflammation, fibrosis, and tumorigenesis.

Recombinant Human Wnt3a Protein (HEK293, C-hFc)

Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family. WNT signaling plays key roles in the control of development, homeostasis, and regeneration of many essential organs and tissues.

Recombinant Mouse IL-15 (E. coli, N-His)

Interleukin-15 (IL-15) is a 14-15 kDa glycoprotein with immune regulatory functions in many diverse cell types. As a pleiotropic cytokine, IL-15 mediates the crosstalk between innate immunity and adaptive immunity whose principal role is to kill virally infected cells. IL-15 plays a crucial role in the development, differentiation, and survival of NK cells.

Recombinant Mouse C3a (E. coli)

Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways.

  Catalog
Abmole Inhibitor Catalog




Keywords: Recombinant Mouse Apolipoprotein E (Mammalian, C-6His), Apo-E; APOE supplier, Recombinant Proteins, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.