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Recombinant Mouse Adiponectin (E. coli)

Cat. No. M21609

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse Adiponectin (E. coli) Structure
Synonym:

Acrp-30; GBP-28; Apm-1

Size Price Availability
10ug USD 160  USD160 1-2 Weeks
50ug USD 385  USD385 1-2 Weeks
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Adiponectin is a hormone mainly produced by adipocytes. Adiponectin forms a homotrimer and exists as higher order multimers in vivo. Adiponectin receives a lot of attention because of its anti-diabetic, anti-atherosclerotic, and anti-inflammatory properties. Adiponectin increases the expression of molecules involved in fatty acid transport, combustion of fatty acid, and energy dissipation, and increases insulin sensitivity of the body. Decreased levels of Adiponectin are associated with hypertension, cardiovascular diseases, and metabolic syndromes.

Measured by a cell growth inhibitory assay using M1 cells, the ED50 is < 5.0 µg/ml, corresponding to a specific activity of > 2.0 × 102 units/mg.

Apparent Molecular Weight: ~24.6 kDa, on SDS-PAGE under reducing conditions.

Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Duc-Vinh Pham, et al. J Exp Clin Cancer Res. Adiponectin triggers breast cancer cell death via fatty acid metabolic reprogramming

[2] Pingping Luo, et al. Acta Pharm Sin B. S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling

[3] Xiruo Li, et al. Proc Natl Acad Sci U S A. Mechanisms by which adiponectin reverses high fat diet-induced insulin resistance in mice

[4] Qi Guo, et al. Diabetologia. Adiponectin treatment improves insulin resistance in mice by regulating the expression of the mitochondrial-derived peptide MOTS-c and its response to exercise via APPL1-SIRT1-PGC-1α

[5] Weihong Li, et al. Biol Reprod. Recombinant adiponectin alleviates abortion in mice by regulating Th17/Treg imbalance via p38MAPK-STAT5 pathway

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Keywords: Recombinant Mouse Adiponectin (E. coli), Acrp-30; GBP-28; Apm-1 supplier, Cytokines and Growth Factors, inhibitors, activators

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