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Recombinant Human TGF-β2 Protein

Cat. No. M9988

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human TGF-β2 Protein Structure
Synonym:

rhTGF-β2; TGF-beta2

Size Price Availability Quantity
10ug USD 480  USD480 In stock
50ug USD 1250  USD1250 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Recombinant Human TGF-β2 Protein is a multifunctional cytokine that regulates cell proliferation, growth, differentiation and movement, as well as the synthesis and deposition of extracellular matrix. The three mammalian subtypes, transforming growth factor-β, transforming growth factor-β1, β2, and β3, send signals through the same receptor, causing similar biological responses. TGF-β2 has an inhibitory effect on IL-2-dependent T cell growth, and may exert an autocrine function through immune surveillance that inhibits tumor growth.

Measured in a cell proliferation assay using mouse HT-2 cells, the ED50 is < 0.2 ng/ml.

Expression host is Human Cells


Accession: P61812

Endotoxin < 1 EU/µg

Apparent Molecular Weight: ~12.7 kDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution in 4 mM HCl.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Wanda E Medina-Ortiz, et al. Invest Ophthalmol Vis Sci. Cellular fibronectin expression in human trabecular meshwork and induction by transforming growth factor-β2

[2] Siegfried G Priglinger, et al. Invest Ophthalmol Vis Sci. Keratinocyte transglutaminase in proliferative vitreoretinopathy

[3] Johannes Gottanka, et al. Invest Ophthalmol Vis Sci. Effects of TGF-beta2 in perfused human eyes

[4] F J Kelly, et al. J Am Soc Nephrol. Acute and chronic renal effects of recombinant human TGF-beta2 in the rat

[5] J T Thompson, et al. Ophthalmology. Comparison of recombinant transforming growth factor-beta-2 and placebo as an adjunctive agent for macular hole surgery

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Keywords: Recombinant Human TGF-β2 Protein, rhTGF-β2; TGF-beta2 supplier, Cytokines and Growth Factors, inhibitors, activators

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