Free shipping on all orders over $ 500

Recombinant Human SCARB2 (HEK293, C-6His)

Cat. No. M21619

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human SCARB2 (HEK293, C-6His) Structure
Synonym:

Scavenger Receptor Class B Member 2

Size Price Availability Quantity
10ug USD 230  USD230 In stock
50ug USD 620  USD620 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
Biological Activity

Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Recombinant Human Scavenger Receptor Class B Member 2 (SCARB2) is produced by Mammalian expression system and the target gene encoding Arg27-Thr432 is expressed with a 6His tag at the C-terminus. SCARB2 may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. In addition, SCARB2 also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.

Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in distilled water to a concentration of 100μg/ml
Storage Stored at ≤ -20°C, stable for one year after receipt
References

[1] Hai-Vy Vo-Nguyen, et al. Iran J Sci Technol Trans A Sci. Recombinant Human SCARB2 Expressed in Escherichia coli and its Potential in Enterovirus 71 Blockage

[2] T Xu, et al. Acta Virol. Prokaryotic expression and identification of scavenger receptor B2

[3] Xuyuan Zhang, et al. Protein Cell. The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection

[4] Xiaojun Li, et al. Virol J. Establishment of cell lines with increased susceptibility to EV71/CA16 by stable overexpression of SCARB2

[5] Yi-Wen Lin, et al. PLoS One. Human SCARB2-mediated entry and endocytosis of EV71

Related Cytokines and Growth Factors Products
Recombinant Human GDF-15 Protein (HEK293 N-hFc)

Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily. GDF-15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.

Recombinant Human FGFR1 Protein (HEK293, C-His)

FGFR1, also known as CD331, is a full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain.

Recombinant Human FGFR2 Protein (HEK293, C-His)

FGFR2, also known as CD332, acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts.

Recombinant Mouse BMP-4 Protein (E. coli, C-His)

Bone Morphogenetic Protein-4 (BMP-4) is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP-4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog to establish a dorsal-ventral axis for the differentiation of later structures.

Recombinant Human Coagulation Factor X (HEK293, C-Fc)

Coagulation factor X, belongs to the peptidase S1 family. Coagulation factor X is initially synthesized in the liver. Coagulation factor X is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

  Catalog
Abmole Inhibitor Catalog




Keywords: Recombinant Human SCARB2 (HEK293, C-6His), Scavenger Receptor Class B Member 2 supplier, Cytokines and Growth Factors, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.