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Recombinant Human SCARB2 (HEK293, C-6His)

Cat. No. M21619

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human SCARB2 (HEK293, C-6His) Structure
Synonym:

Scavenger Receptor Class B Member 2

Size Price Availability Quantity
10ug USD 230  USD230 In stock
50ug USD 620  USD620 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
Biological Activity

Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Recombinant Human Scavenger Receptor Class B Member 2 (SCARB2) is produced by Mammalian expression system and the target gene encoding Arg27-Thr432 is expressed with a 6His tag at the C-terminus. SCARB2 may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. In addition, SCARB2 also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.

Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in distilled water to a concentration of 100μg/ml
Storage Stored at ≤ -20°C, stable for one year after receipt
References

[1] Hai-Vy Vo-Nguyen, et al. Iran J Sci Technol Trans A Sci. Recombinant Human SCARB2 Expressed in Escherichia coli and its Potential in Enterovirus 71 Blockage

[2] T Xu, et al. Acta Virol. Prokaryotic expression and identification of scavenger receptor B2

[3] Xuyuan Zhang, et al. Protein Cell. The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection

[4] Xiaojun Li, et al. Virol J. Establishment of cell lines with increased susceptibility to EV71/CA16 by stable overexpression of SCARB2

[5] Yi-Wen Lin, et al. PLoS One. Human SCARB2-mediated entry and endocytosis of EV71

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Keywords: Recombinant Human SCARB2 (HEK293, C-6His), Scavenger Receptor Class B Member 2 supplier, Cytokines and Growth Factors, inhibitors, activators

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