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Recombinant Human RANK (HEK293, C-6His)

Cat. No. M21714

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human RANK (HEK293, C-6His) Structure
Synonym:

Receptor activator of NF-KB; CD265

Size Price Availability Quantity
10ug USD 200  USD200 In stock
50ug USD 470  USD470 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Recombinant Human RANK (C-6His) is produced by Mammalian expression system and the target gene encoding Ile30-Pro212 is expressed with a 6His tag at the C-terminus. Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation.

Accession: Q9Y6Q6

APMol Mass: 25-30 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Solubility (25°C) Dissolve the lyophilized protein in distilled water.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt
References

[1] A Llop-Guevara, et al. Ann Oncol. Association of RAD51 with homologous recombination deficiency (HRD) and clinical outcomes in untreated triple-negative breast cancer (TNBC): analysis of the GeparSixto randomized clinical trial

[2] Tomohiko Sano, et al. BMC Musculoskelet Disord. Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration

[3] Yilei Wei, et al. BMC Biotechnol. Heterologous expression, purification and function of the extracellular domain of human RANK

[4] I Silva, et al. Acta Reumatol Port. Rank/Rankl/opg: literature review

[5] Shiqian Zhang, et al. Arch Biochem Biophys. The affinity of human RANK binding to its ligand RANKL

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Keywords: Recombinant Human RANK (HEK293, C-6His), Receptor activator of NF-KB; CD265 supplier, Cytokines and Growth Factors, inhibitors, activators

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