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Recombinant Human Periostin Protein (HEK293, C-6His)

Cat. No. M43835

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human Periostin Protein (HEK293, C-6His) Structure
Synonym:

OSF-2; POSTN; Periostin

Size Price Availability Quantity
10ug USD 190  USD190 In stock
50ug USD 430  USD430 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

POSTN (Periostin, OSF-2) is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumor suppressor. It is synthesized by smooth muscle cells, fibroblasts and osteoblasts, as well as in the periosteum and periodontal ligament. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells.

Recombinant Human POSTN (Periostin, OSF-2) expressed the target gene encoding Asn22-Gln779 with a 6His tag at the C-terminus.


Accession: Q15063-2

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 85-90 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Carolina Balbi, et al. Theranostics. An exosomal-carried short periostin isoform induces cardiomyocyte proliferation

[2] Raphaёl Kormann, et al. J Am Soc Nephrol. Periostin Promotes Cell Proliferation and Macrophage Polarization to Drive Repair after AKI

[3] Seong-Joon Koh, et al. Carcinogenesis. Matricellular protein periostin promotes colitis-associated colon tumorigenesis in mice

[4] Miwa Kanaoka, et al. J Dermatol Sci. Pro-fibrotic phenotype of human skin fibroblasts induced by periostin via modulating TGF-β signaling

[5] M Matsuzawa, et al. J Periodontal Res. Periostin of human periodontal ligament fibroblasts promotes migration of human mesenchymal stem cell through the αvβ3 integrin/FAK/PI3K/Akt pathway

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Keywords: Recombinant Human Periostin Protein (HEK293, C-6His), OSF-2; POSTN; Periostin supplier, Cytokines and Growth Factors, inhibitors, activators

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