All AbMole products are for research use only, cannot be used for human consumption.
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as LOX1, is a receptor protein that belongs to the C-type lectin superfamily. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. Ox-LDL receptor 1 is expressed at high levels in endothelial cells and vascular rich organs such as placenta, lung, liver, brain, intima of the aorta, bone marrow, spinal cord and substantia nigra. Ox-LDL receptor 1 expression is induced by inflammatory cytokines such as TNF, IFNG, and IL6 in the context of hyperlipidemia, hypertension, and diabetes. Ox-LDL receptor-1 mediates the recognition, internalization, and degradation of oxidation-modified low-density lipoproteins (OxLDL) by vascular endothelial cells.
Recombinant Human OLR1/LOX1 expressed the target gene encoding Ser61-Gln273 with a 6His tag at the C-terminus.
Accession: P78380
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 30-35 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[5] Bertram Pitt. Circulation. A new HOPE for aldosterone blockade?
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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