All AbMole products are for research use only, cannot be used for human consumption.
Species: Human
Expression system: CHO
Purity: SDS-PAGE analysis, > 95%, HIGH performance liquid chromatography analysis, > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: 8~ 10kda, sds-page under reduction conditions
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.
Bioactivity: ED50 < 100.0 ng/ mL, calcium flux was measured using CHO/Gα15 cells expressing CCR5. Mip-1 α polymorphism is associated with HIV susceptibility or drug resistance. Recombinant MIP-1 α induces dose-dependent suppression of HIV and SIV infection. In response to endogenous and exogenous factors such as interleukin-1 β, interferon -γ, and gram-positive bacterial lipoteichoic acid, monocytes can secrete large amounts of MIP-1α. Mip-1 α enhances the adhesion of T lymphocytes, monocytes, and neutrophils to vascular cell adhesion molecule 1. In addition, miP-1 α accelerates tissue repair by chemically attracting macrophages during trauma.
| Solubility (25°C) | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] C Blanpain, et al. Blood. CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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