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Recombinant Human LBP (HEK293, C-6His)

Cat. No. M40901

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human LBP (HEK293, C-6His) Structure
Synonym:

Lipopolysaccharide-Binding Protein

Size Price Availability Quantity
10ug USD 210  USD210 In stock
50ug USD 600  USD600 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Lipopolysaccharide binding protein (LBP) is a plasma protein, it is involved in the acute-phase immunologic response to gram-negative bacterial infections. LBP binds LPS and interacts with the CD14 receptor, most likely playing a role in regulating LPS-dependent monocyte responses. LBP is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation.

Recombinant Human Lipopolysaccharide-Binding Protein expressed the target gene encoding Ala26-Val481 with a 6His tag at the C-terminus.


Accession: P18428

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 64 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 1mM EDTA, pH 8.0.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Simon Koplev et al. Nat Cardiovasc Res. A mechanistic framework for cardiometabolic and coronary artery diseases

[2] Y C Henderson et al. Placenta. Human LBP-32/MGR is a repressor of the P450scc in human choriocarcinoma cell line JEG-3

[3] Ningwu Huang et al. Mol Endocrinol. LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells

[4] A V Sorokin et al. Biochemistry (Mosc). Human recombinant laminin-binding protein: isolation, purification, and crystallization

[5] S Lengacher et al. J Inflamm. Reactivity of murine and human recombinant LPS-binding protein (LBP) within LPS and gram negative bacteria

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Keywords: Recombinant Human LBP (HEK293, C-6His), Lipopolysaccharide-Binding Protein supplier, Cytokines and Growth Factors, inhibitors, activators

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