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Recombinant Human IP-10/CXCL10 (E. coli)

Cat. No. M15038

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human IP-10/CXCL10 (E. coli) Structure
Synonym:

Small inducible cytokine B10; CXCL10

Size Price Availability Quantity
10ug USD 155  USD155 In stock
50ug USD 330  USD330 In stock
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Quality Control & Documentation
  • Purity: >95% , Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Species: Human
Expression system: E. coli
Purity: SDS-PAGE analysis > 95%, HPLC analysis > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: ~8.6 kDa, sdS-PAGE under reduction conditions
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.


Biological activity: When the concentration of H-VEGF was 2.5 ng/ mL, the ED50 measured by HUVEC cell proliferation assay was less than 0.2 μg/ mL, and the corresponding specific activity was > 5.0 × 103 IU/mg. Other cell types expressing IP-10 include activated T lymphocytes, spleen cells, keratinocytes, osteoblasts, astrocytes, and smooth muscle cells. Ip-10 is also expressed in psoriasis and leprosy lesions. The mouse homolog crG-2 of human IP-10 has been cloned and shown to share approximately 67% of the amino acid sequence with human IP-10.

Chemical Information
Solubility (25°C) It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml.
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] A M Cole, et al. J Immunol. Cutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity

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Keywords: Recombinant Human IP-10/CXCL10 (E. coli), Small inducible cytokine B10; CXCL10 supplier, Cytokines and Growth Factors, inhibitors, activators

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