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Recombinant Human IL32 (E.coli)

Cat. No. M21166
Recombinant Human IL32 (E.coli) Structure
Synonym:

Natural killer cells protein 4;Tumor necrosis factor alpha-inducing factor

Size Price Availability Quantity
50ug USD 320  USD400 In stock
100ug USD 576  USD720 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >95%
  • COA
  • MSDS
Biological Activity

Genus: Human
Expression system: E.coli
Purity: >95% as determined by SDS-PAGE
Protein Construct: DNA sequence encoding human IL32 (Ala31-Lys234) fused with His tag
Predicted molecular weight: 25.56 kDa
Storage and Stability: Use a manually thawed refrigerator to avoid repeated freeze-thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for 12 months from date of receipt.

Bioactivity: It induces various cytokines such as TNFA/TNF-α and IL8. it activates the typical cytokine signaling pathways NF-kappa-B and p38 MAPK.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight
Formula
CAS Number
Purity >95%
Solubility Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products
please refer to it for details.
Storage at -20°C
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Keywords: Recombinant Human IL32 (E.coli), Natural killer cells protein 4;Tumor necrosis factor alpha-inducing factor supplier, Cytokines, inhibitors

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