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Recombinant Human IL31RA Protein (HEK293, C-hFc)

Cat. No. M40924

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human IL31RA Protein (HEK293, C-hFc) Structure
Synonym:

interleukin 31 receptor A

Size Price Availability Quantity
50ug USD 525  USD525 In stock
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Quality Control & Documentation
  • Purity: >90%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

The recombinant human IL31RA consists 735 amino acids and predicts a molecular mass of 83.5 kDa. A DNA sequence encoding the human IL31RA (Met1-Ser516) was expressed with the Fc region of human IgG1 at the C-terminus.

Immobilized human IL31-His at 10μg/mL (100μL/well) can bind human IL31RA-Fc, the EC50 of human IL31RA-Fc is 0.4-1.6 μg/mL.


Endotoxin < 1 EU/µg

Lyophilized from sterile PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 250 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Tal Kan et al. J Immunother Cancer. IL-31 induces antitumor immunity in breast carcinoma

[2] Shiri Davidi et al. Oncotarget. The antiangiogenic role of the pro-inflammatory cytokine interleukin-31

[3] Emilie Venereau et al. J Biol Chem. Definition and characterization of an inhibitor for interleukin-31

[4] Yuxin Zheng et al. 3 Biotech. Canine interleukin-31 binds directly to OSMRβ with higher binding affinity than to IL-31RA

[5] Chun-Kwok Wong et al. PLoS One. Activation of eosinophils interacting with dermal fibroblasts by pruritogenic cytokine IL-31 and alarmin IL-33: implications in atopic dermatitis

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Keywords: Recombinant Human IL31RA Protein (HEK293, C-hFc), interleukin 31 receptor A supplier, Cytokines and Growth Factors, inhibitors, activators

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