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Recombinant Human IL-5 Protein (IL-5) is a member of the interleukin family with length of 115 amino acids. Interleukin 5 (IL-5) is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered as a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony stimulating factor.
The recombinant human IL5 consists of 115 amino acids and predicts a molecular mass of 13.1 KDa. A DNA sequence encoding the human IL5 (Ile20-Ser134) was expressed.
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells, the ED50 for this effect is typically 0.1-0.5 ng/mL.
Accession: P05113
Endotoxin < 1 EU/µg
Lyophilized from sterile PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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