All AbMole products are for research use only, cannot be used for human consumption.
Recombinant Human IL-22 Protein (Interleukin-22) is produced by T lymphocytes, inhibits Th2 cells from producing IL-4, and induces acute reactants in the liver and pancreas. IL-22 is a member of the IL-10 regulatory cytokine family, including IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family have partial homology in their amino acid sequences, but they are different in biological function. IL-22 signal is transmitted through a receptor system composed of IL-10Rβ/CRF 2-4 and IL-22R, both of which are members of the class II cytokine receptor family.
The recombinant human IL-22 protein contains 152 amino acids and the predicted molecular weight is 17.6kd.
IL-22's biological activity depends on its ability to activate STAT in receptor ligand interactions. Its ability to induce the secretion of IL-10 colon cancer cells as an indicator of the expected ED50. This effect is 0.7 ~ 1.0 ng/mL.
Endotoxin < 0.1EU/ug
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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