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Recombinant Human IL-13 Protein

Cat. No. M9982
Recombinant Human IL-13 Protein Structure
Synonym:

Interleukin-13; rhIL-13

Size Price Availability Quantity
50ug USD 437.4  USD486 In stock
100ug USD 743.4  USD826 In stock
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Quality Control
  • Current batch:
  • Purity ≥95%, Endotoxin <0.2 EU/ug
  • COA
  • MSDS
Biological Activity

Recombinant Human IL-13 Protein is an immunomodulatory cytokine, mainly produced by activated Th2 cells, mast cells and NK cells. Interleukin-13 plays an important role in the elimination of gastrointestinal parasites. rhIL-13 has anti-inflammatory effects on monocytes and macrophages, and inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to promote B cells Proliferate and induce isoform conversion, thereby increasing the production of IgE. Blocking IL-13 activity can inhibit the pathophysiology of asthma. Human and mouse IL-13 are cross-species responses.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight
Formula
CAS Number
Purity ≥95%, Endotoxin <0.2 EU/ug
Solubility Water
Saline
PBS
Storage 2-8°C, dry, sealed
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Recombinant Human IL-13 Protein, Interleukin-13; rhIL-13 supplier, Cytokines, inhibitors

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