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Insulin-like growth factor I (IGF1) binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions.
Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is 20-100 ng/ml.
| Molecular Weight | 7645.68 |
| Formula | C331H512N94O101S7 |
| CAS Number | 68562-41-4 |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration of 100μg/ml |
| Storage | Stored at ≤ -20°C, stable for one year after receipt |
[3] George M Bright. Growth Horm IGF Res. Recombinant IGF-I: Past, present and future
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Products are for research use only. Not for human use. We do not sell to patients.
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