All AbMole products are for research use only, cannot be used for human consumption.
Recombinant Human IGF-1 LR3 Protein is a mitogenic polypeptide growth factor that can stimulate the proliferation and survival of various cells, including muscle, bone and cartilage tissue. Recombinant Human IGF-1 LR3 is a recombinant analog of human IGF-I and consists of the complete IGF-I sequence , The third glutamic acid is replaced by arginine, and the N-terminal peptide extends 13 amino acids. The isolated IGF-ILR 3 designed for higher biological efficacy has an increased half-life and an aversion to the binding of natural proteins in the body, making it an ideal choice for research and large-scale cultivation.
The recombinant human IGF1 consists of 83 amino acids and predicts a molecular mass of 9.1 kDa. A DNA sequence encoding the human IGF1 (P05019-1) (Gly49-Ala118, with mutation Glu 51 Arg) was expressed with a 13 amino acids (MFPAMPLSSLFVN) at its N-terminus.
Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells, the ED50 for this effect is typically 1.5-6 ng/mL.
Accession: P05019-1
Endotoxin < 0.1 EU/µg
Lyophilized from sterile PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| Related Cytokines and Growth Factors Products |
|---|
| Recombinant Human FGFR1 Protein (HEK293, C-His)
FGFR1, also known as CD331, is a full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. |
| Recombinant Human FGFR2 Protein (HEK293, C-His)
FGFR2, also known as CD332, acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts. |
| Recombinant Mouse BMP-4 Protein (E. coli, C-His)
Bone Morphogenetic Protein-4 (BMP-4) is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP-4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog to establish a dorsal-ventral axis for the differentiation of later structures. |
| Recombinant Human Coagulation Factor X (HEK293, C-Fc)
Coagulation factor X, belongs to the peptidase S1 family. Coagulation factor X is initially synthesized in the liver. Coagulation factor X is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. |
| Recombinant Human FGF-8b Protein (E. coli)
Recombinant Human FGF-8b Protein is a heparin-binding growth factor, which plays a core role in prenatal development, postnatal growth and regeneration of various tissues by promoting cell proliferation and other effect. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
