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Human Granulocyte Colony Stimulating Factor (G-CSF) is a pleiotropic cytokine, mainly produced by monocytes and macrophages upon activation by endotoxin, TNF-α and IFN-γ. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. G-CSF is cytokine that acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. In addition it may function in some adhesion or recognition events at the cell surface. Human G-CSF is 73 % identical at the amino acid level to murine G-CSF and the two proteins show species cross-reactivity.
| Solubility (25°C) | Water Saline PBS |
| Storage | -20°C, sealed |
[3] G D Demetri, et al. Blood. Granulocyte colony-stimulating factor and its receptor
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