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Species: Human
Expression system: Human Cells
Purity: > 95% as determined by reduced SDS-PAGE
Endotoxin: LAL test measured less than 0.1 ng/µg (1eu /µg)
Molecular weight: 36.7KDa
Storage and stability: Freeze-dried protein should be stored at < -20℃, but stable at room temperature for 3 weeks. The recombinant protein solution can be stored at 4-7℃ for 2-7 days. The bisector of the recombinant sample was stable at < -20°C for 3 months.
Bioactivity: Galectin-9 is a cytoplasmic protein containing two galectin-domains. Galactin-9 is an S-type lectin that is overexpressed in Hodgkin's disease tissues. Galactosidine -9 binds galactoside and has a high affinity for Forssman five sugars. Galactin-9 plays a role in thymocyte-epithelial interactions, is relevant to thymus biology, and inhibits cell proliferation. Galectin-9, a ligand of HAVCR2/TIM3, induces the death of T-helper type 1 lymphocytes (Th1). In addition, Galectin-9 inhibits tumor cell metastasis by interfering with CD44, VCAM-1, Integrin α4β1 and other factors.
| Solubility (25°C) | It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Valerie R Wiersma, et al. Med Res Rev. Therapeutic potential of Galectin-9 in human disease
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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