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Recombinant Human Galectin 9 (Human Cells, C-6His)

Cat. No. M21457

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human Galectin 9 (Human Cells, C-6His) Structure
Synonym:

Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21

Size Price Availability Quantity
10ug USD 182  USD182 In stock
50ug USD 400  USD400 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin<1 EU/µg
  • COA
  • MSDS
Biological Activity

Species: Human
Expression system: Human Cells
Purity: > 95% as determined by reduced SDS-PAGE
Endotoxin: LAL test measured less than 0.1 ng/µg (1eu /µg)
Molecular weight: 36.7KDa
Storage and stability: Freeze-dried protein should be stored at < -20℃, but stable at room temperature for 3 weeks. The recombinant protein solution can be stored at 4-7℃ for 2-7 days. The bisector of the recombinant sample was stable at < -20°C for 3 months.


Bioactivity: Galectin-9 is a cytoplasmic protein containing two galectin-domains. Galactin-9 is an S-type lectin that is overexpressed in Hodgkin's disease tissues. Galactosidine -9 binds galactoside and has a high affinity for Forssman five sugars. Galactin-9 plays a role in thymocyte-epithelial interactions, is relevant to thymus biology, and inhibits cell proliferation. Galectin-9, a ligand of HAVCR2/TIM3, induces the death of T-helper type 1 lymphocytes (Th1). In addition, Galectin-9 inhibits tumor cell metastasis by interfering with CD44, VCAM-1, Integrin α4β1 and other factors.

Chemical Information
Solubility (25°C) It is not recommended to reconstitute to a concentration less than 100μg/ml.
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Asahiro Morishita, et al. Oncol Rep. Galectin‑9 suppresses the tumor growth of colon cancer in vitro and in vivo

[2] Zhi-Hui Li, et al. Front Immunol. Galectin-9 Alleviates LPS-Induced Preeclampsia-Like Impairment in Rats via Switching Decidual Macrophage Polarization to M2 Subtype

[3] Mohamed Abdel-Mohsen, et al. PLoS Pathog. Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation

[4] Shintaro Fujihara, et al. Recent Pat Endocr Metab Immune Drug Discov. Galectin-9 in cancer therapy

[5] Valerie R Wiersma, et al. Med Res Rev. Therapeutic potential of Galectin-9 in human disease

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Keywords: Recombinant Human Galectin 9 (Human Cells, C-6His), Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21 supplier, Cytokines and Growth Factors, inhibitors, activators

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