Species: Human
Expression system: Expi293
Purity: SDS-PAGE analysis > 95%, HPLC analysis > 95%
Endotoxin: LAL method for determination of protein ≤1 EU/μg
Apparent molecular weight: 30 ~ 45 kDa, reduced under SDS-PAGE
Storage and stability: After receiving, the product remains stable at -70°C or -20°C for up to 6 months. Avoid repeated freeze-thaw cycles
Bioactivity: 0.2 μg/ mL (100 μ L /Well) immobilized human EpCAM. The dose-response curve of anti-Trop1 antibody EC50 was 8.7 ng/ mL by ELISA. Epithelial cell adhesion molecule (EpCAM), also known as KS1/4, GP40, GA733-2, 17-1A, and TROP-1, is a 40 kDa transmembrane glycoprotein, It consists of an extracellular domain of 242 amino acids (AA) (with two EGF-like repeats), a 23 AA transmembrane segment, and a 26 AA cytoplasmic domain.
| Solubility (25°C) | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Recombinant Proteins Products |
|---|
| Recombinant Mouse IL-1RL2 Protein (Mammalian, C-6His)
Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene, belongs to the interleukin-1 receptor family. IL1RL2 is the receptor for interleukin-36. Recombinant Mouse Interleukin-1 Receptor-like 2 expressed the target gene encoding Asp22-Arg338(Ala158Val) with a 6His tag at the C-terminus. |
| Recombinant Human/Mouse/Rat GDF-11 Protein (Mammalian)
Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. |
| Recombinant Human IL31RA Protein (HEK293, C-hFc)
The recombinant human IL31RA consists 735 amino acids and predicts a molecular mass of 83.5 kDa. A DNA sequence encoding the human IL31RA (Met1-Ser516) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Recombinant Human IL31RA Protein (HEK293, C-His)
The recombinant human IL31RA consists 508 amino acids and predicts a molecular mass of 58.2 kDa. A DNA sequence encoding the human IL31RA (Met1-Ser516) was expressed with a polyhistidine tag at the C-terminus. |
| Recombinant Human IL-1β Protein (CHO)
Interleukin 1 beta (IL-1β) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
