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RBC8 is a ralA and RalB GTPase inhibitor (EC50 ~3.5 μM). Inhibits the binding of Ral to RaLBP1. Exhibits no detectable inhibition of Ras or RhoA activity. Suppresses growth of xenograft tumors in mice. Cell permeable.
| Molecular Weight | 424.45 |
| Formula | C25H20N4O3 |
| CAS Number | 361185-42-4 |
| Solubility (25°C) | DMSO 42.44 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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