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Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependent, with higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents.
| Molecular Weight | 398.45 |
| Formula | C17H19FN2O2 · CH3SO3H |
| CAS Number | 202825-45-4 |
| Solubility (25°C) | Water: ≥15 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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