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Dexfadrostat

Cat. No. M27663

All AbMole products are for research use only, cannot be used for human consumption.

Dexfadrostat Structure
Synonym:

(R)-Fadrozole; (R)-CGS 16949A free base; FAD286

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Quality Control & Documentation
Biological Activity

Dexfadrostat ((R)-Fadrozole) is a potent nonsteroidal inhibitor. Dexfadrostat also inhibits human placental aromatase (pIC50 = 6.17) and aldosterone biosynthesis. Dexfadrostat reverses cardiac fibrosis in spontaneously hypertensive heart failure rats..

Chemical Information
Molecular Weight 223.27
Formula C14H13N3
CAS Number 102676-87-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Paolo Mulatero, et al. Br J Clin Pharmacol. CYP11B2 inhibitor dexfadrostat phosphate suppresses the aldosterone-to-renin ratio, an indicator of sodium retention, in healthy volunteers

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Keywords: Dexfadrostat, (R)-Fadrozole; (R)-CGS 16949A free base; FAD286 supplier, inhibitors, activators

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